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Edward Jenner was an English doctor and scientist who created the world\u2019s first vaccine<\/a>, the smallpox vaccine. The eighth child of a Gloucestershire churchman, the father of vaccinology saved the lives of millions of people around the world. He died of an apparent stroke, aged 73, and was survived by two of his three children.<\/p>\n <\/p><\/div> <\/section> In my school days. But it was not until after 2005, when I became more involved in vaccine development, that I learned more about his story and all that he achieved.<\/p>\n He was a country doctor, but also a naturalist, and in his first paper he observed how the cuckoo threw other eggs out of nests \u2013 so he was obviously a naturally curious person. He liked to understand how things worked and was also keen on communicating his findings. At heart, I think he was a scientist despite working as a doctor.<\/p>\n He\u2019s known as the \u201cFather of Vaccinology\u201d, and for good reason. Everyone knows how he vaccinated his gardener\u2019s eight-year-old son, James Phipps, with cowpox taken from a milkmaid. He did it because he wanted to stop another practice: deliberately infecting children with a small amount of the smallpox virus to protect them against smallpox. This was an unpleasant procedure \u2013 it had been done to him as a child \u2013 and he wanted to find a better, safer way of protecting people against smallpox. And that\u2019s why he used cowpox.<\/p>\n Persisting with publishing his findings on the smallpox vaccine until everybody knew about them, which had huge benefits for public health. In his day, the disease killed around one in 10 of the population, and as many as one in five in towns. What he did that was so important was to test his vaccine \u2013 by trying to infect James with smallpox after inoculating him \u2013 and test it again, and then write up his findings on a number of cases and present them to the Royal Society. He went on to vaccinate as many local people as possible: both the gentry and those too poor to pay, in a building in his garden known as the Temple of Vaccinia. Smallpox is the only human disease that has been eradicated and that all goes back to his work.<\/p>\n I have also initiated development of a vaccine, which went into clinical testing and was then proven to be effective. The regulatory and ethical requirements to do this are very different now, and I wonder what Jenner would have made of them. But I am sure he would have been cheering us on.<\/p>\n I\u2019d like to know whether he thought vaccination is all about protecting the individual or the whole population.<\/p>\n Dame Sarah Gilbert is a professor of vaccinology at Oxford University. She co-developed the Oxford-AstraZeneca Covid-19 vaccine with the Oxford Vaccine Group<\/strong><\/p>\n This content first appeared in the January 2022 issue of BBC History Magazine<\/a><\/strong><\/em><\/p>\nWhen did you first hear about Edward Jenner?<\/h3>\n
What kind of person was he?<\/h3>\n
What made Jenner a hero?<\/h3>\n
What was his finest hour?<\/h3>\n
Can you see any parallels between Jenner\u2019s life and your own?<\/h3>\n
What would you ask Jenner if you could meet him?<\/h3>\n