{"id":18182,"date":"2022-10-11T00:00:00","date_gmt":"2022-10-10T22:00:00","guid":{"rendered":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/?post_type=purple_issue&#038;p=18182"},"modified":"2022-11-02T12:50:38","modified_gmt":"2022-11-02T11:50:38","slug":"do-painkillers-work-differently-for-different-people","status":"publish","type":"post","link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/2022\/10\/11\/do-painkillers-work-differently-for-different-people\/","title":{"rendered":"Do painkillers work differently for different people?"},"content":{"rendered":"\n<h2 class=\"has-text-align-center\"><strong>Do painkillers work differently for different people?<\/strong><\/h2>\n\n<p class=\"has-text-align-center intro\">GEOFF WINSTANLEY, BLANDFORD FORUM <\/p>\n\n<div class=\"no-tts wp-block-image article-in-image photo\"><figure class=\"no-tts aligncenter size-large\"><img loading=\"lazy\" width=\"1024\" height=\"832\" src=\"https:\/\/dj9jqhxgw9833.cloudfront.net\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-1024x832.jpg\" alt=\"\" class=\"no-tts wp-image-18507\" srcset=\"https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-1024x832.jpg 1024w, https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-300x244.jpg 300w, https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-768x624.jpg 768w, https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview.jpg 1231w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n<p class=\"article-full-body sans-serif\">In short \u2013 yes, it is thought that there is some individual variation in the response to a particular painkiller. But pain is a complex perception. Sensation is influenced by so many factors, including variation in the type of pain, genetic factors, stress-related physiological responses, socio-cultural influences, our prior experience, emotional state, and by the context it occurs. So it is difficult to attribute our response to a painkiller to something as simple as painkiller receptors alone, but these are likely to play a part. <em><strong>NM <\/strong><\/em><\/p>\n\n<section class=\"wp-block-uagb-section uagb-section__wrap uagb-section__background-color uagb-block-c7e76bb7-8001-4b0b-b8fb-d36d1049d738\"><div class=\"uagb-section__overlay\"><\/div><div class=\"uagb-section__inner-wrap\">\n<p class=\"has-text-align-center has-ccp-primary-light-color has-text-color\"><span class=\"has-inline-color has-ccp-primary-light-color\">Email your questions to<\/span> <br><a href=\"mailto:questions@sciencefocus.com\">questions@sciencefocus.com<\/a> <br><span class=\"has-inline-color has-ccp-primary-light-color\">or submit on Twitter<\/span> <br><a href=\"https:\/\/twitter.com\/sciencefocus\" data-type=\"URL\" data-id=\"https:\/\/twitter.com\/sciencefocus\">@sciencefocus<\/a><\/p>\n<\/div><\/section>\n\n<p class=\"footer\">IMAGE: GETTY IMAGES<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Do painkillers work differently for different people? GEOFF WINSTANLEY, BLANDFORD FORUM In short \u2013 yes, it is thought that there is some individual variation in the response to a particular painkiller. But pain is a complex perception. Sensation is influenced by so many factors, including variation in the type of pain, genetic factors, stress-related physiological [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":18507,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ub_ctt_via":"","purple_page_number":"76","purple_custom_meta_purple_page_number":"76","purple_seq_number":"1","purple_custom_meta_purple_seq_number":"1","purple_source_article":"article_76-1.xml","purple_custom_meta_purple_source_article":"article_76-1.xml","purple_source_issue":"October-2022","purple_custom_meta_purple_source_issue":"October-2022","purple_external_id":"October-2022-76-1","purple_custom_meta_purple_external_id":"October-2022-76-1","purple_issue_code":"|0000089659||","purple_custom_meta_purple_issue_code":"|0000089659||","purple_android_product":"com.focus.magazine.issue383","purple_custom_meta_purple_android_product":"com.focus.magazine.issue383.2","purple_ios_product":"com.focus.magazine.issue383","purple_custom_meta_purple_ios_product":"com.focus.magazine.issue383.2","purple_web_product":"","purple_custom_meta_purple_web_product":"","purple_publication_id":"0f422ad1-c939-476d-9f82-a410052ad4c3","purple_migrated":"","kt_blocks_editor_width":"","apple_news_api_created_at":"2022-10-11T10:39:00Z","apple_news_article-theme":"","apple_news_api_id":"4e80ab8f-df08-4fca-8cc9-998dc43c97c6","apple_news_api_modified_at":"2022-10-12T08:57:05Z","apple_news_api_revision":"AAAAAAAAAAAAAAAAAAAAAw==","apple_news_api_share_url":"https:\/\/apple.news\/AToCrj98IT8qMyZmNxDyXxg","apple_news_coverimage":0,"apple_news_coverimage_caption":"","apple_news_is_hidden":false,"apple_news_is_paid":true,"apple_news_is_preview":true,"apple_news_is_sponsored":false,"apple_news_maturity_rating":"","apple_news_pullquote":"","apple_news_pullquote_position":"","apple_news_article_theme":"","apple_news_sections":"[]"},"categories":[30],"tags":[15],"apple_news_notices":[],"featured_image_src":"https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview.jpg","author_info":{"display_name":"importmanagerhub@sprylab.com","author_link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/author\/importmanagerhubsprylab-com\/"},"acf":{"readingTimeMinutes":"< 1","apple_news_title":""},"uagb_featured_image_src":{"full":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview.jpg",1231,1000,false],"thumbnail":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-150x150.jpg",150,150,true],"medium":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-300x244.jpg",300,244,true],"medium_large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-768x624.jpg",768,624,true],"large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview-1024x832.jpg",800,650,true],"1536x1536":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview.jpg",1231,1000,false],"2048x2048":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/10\/GettyImages_1043509888_preview.jpg",1231,1000,false]},"uagb_author_info":{"display_name":"importmanagerhub@sprylab.com","author_link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/author\/importmanagerhubsprylab-com\/"},"uagb_comment_info":0,"uagb_excerpt":"Do painkillers work differently for different people? GEOFF WINSTANLEY, BLANDFORD FORUM In short \u2013 yes, it is thought that there is some individual variation in the response to a particular painkiller. But pain is a complex perception. Sensation is influenced by so many factors, including variation in the type of pain, genetic factors, stress-related physiological&hellip;","_links":{"self":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/posts\/18182"}],"collection":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/comments?post=18182"}],"version-history":[{"count":6,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/posts\/18182\/revisions"}],"predecessor-version":[{"id":19519,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/posts\/18182\/revisions\/19519"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/media\/18507"}],"wp:attachment":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/media?parent=18182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/categories?post=18182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/tags?post=18182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}