{"id":6430,"date":"2022-03-10T00:00:00","date_gmt":"2022-03-09T23:00:00","guid":{"rendered":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/?post_type=purple_issue&#038;p=6430"},"modified":"2022-03-23T10:16:04","modified_gmt":"2022-03-23T09:16:04","slug":"cyanide-may-have-played-a-key-role-in-the-origin-of-life-on-earth-and-could-help-us-find-alien-life","status":"publish","type":"post","link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/2022\/03\/10\/cyanide-may-have-played-a-key-role-in-the-origin-of-life-on-earth-and-could-help-us-find-alien-life\/","title":{"rendered":"Cyanide may have played a key role in the origin of life on Earth, and could help us find alien life"},"content":{"rendered":"\n<p class=\"intro\"><strong>The chemical may drive reactions that produce organic molecules<\/strong><\/p>\n\n<p class=\"article-full-body sans-serif\">Though perhaps better known as the lethal substance taken in pill form by captured spies in cheesy thrillers, cyanide may have helped life to evolve on Earth. And looking for signs of it on alien planets could help us to locate life elsewhere in the Universe, chemists at Scripps Research have discovered.<\/p>\n\n<figure class=\"no-tts wp-block-image article-in-image photo\"><img loading=\"lazy\" width=\"2048\" height=\"1239\" src=\"https:\/\/dj9jqhxgw9833.cloudfront.net\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a.jpg\" alt=\"\" class=\"no-tts wp-image-6427\" srcset=\"https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a.jpg 2048w, https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-300x181.jpg 300w, https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-1024x620.jpg 1024w, https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-768x465.jpg 768w, https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-1536x929.jpg 1536w\" sizes=\"(max-width: 2048px) 100vw, 2048px\" \/><figcaption>Cyanide was present in the atmosphere of a young Earth<\/figcaption><\/figure>\n\n<p class=\"article-full-body sans-serif\">The scientists found that the chemical compound, which contains a carbon atom bonded to a nitrogen atom, could have enabled some of the first metabolic reactions on Earth that created carbon-based compounds from carbon dioxide. Metabolic reactions are reactions that generate energy out of food and are essential for sustaining life.<\/p>\n\n<p class=\"article-full-body sans-serif\">\u201cWhen we look for signs of life \u2013 either on the early Earth or on other planets \u2013 we base the search on the biochemistry we know exists in life today. The fact that these same metabolic reactions can be driven by cyanide shows that life can be very <span>different,\u201d said the study\u2019s lead author Ramanarayanan Krishnamurthy, an associate professor of chemistry at the institute.<\/span><\/p>\n\n<p class=\"article-full-body sans-serif\">To make the discovery, the team focused on a set of chemical reactions that combine carbon dioxide and water to create the more complex compounds that are necessary for life, known as the reverse tricarboxylic acid cycle.<\/p>\n\n<p class=\"article-full-body sans-serif\">The cycle is used by some bacteria, but it relies on the use of complex proteins that weren\u2019t present on the planet four billion years ago.<\/p>\n\n<p class=\"article-full-body sans-serif\">As previous studies have shown that <span>certain metals can trigger the same reactions under extremely hot and highly acidic conditions, the Scripps team had a hunch that another chemical may also be able to do so, only under the less violent conditions seen on the early Earth.<\/span><\/p>\n\n<p class=\"article-full-body sans-serif\">They already knew that cyanide was present in the atmosphere back then, so they mapped out a set of reactions that could potentially use cyanide to produce complex organic molecules from carbon dioxide and then tested them in the lab.<\/p>\n\n<p class=\"article-full-body sans-serif\">\u201cIt was scary how simple it was,\u201d said Krishnamurthy. \u201cWe really didn\u2019t have to do anything special, we mixed together these molecules, waited and the reaction happened spontaneously.\u201d Although the experiment doesn\u2019t provide proof that cyanide was involved in this process on the early Earth, it does offer a fresh way of thinking about the origin of life, and perhaps a new means of searching for life on other planets.<\/p>\n\n<p class=\"footer\">Image: Science Photo Library<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The chemical may drive reactions that produce organic molecules<\/p>\n","protected":false},"author":24,"featured_media":6427,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ub_ctt_via":"","purple_page_number":"18","purple_custom_meta_purple_page_number":"18","purple_seq_number":"1","purple_custom_meta_purple_seq_number":"1","purple_source_article":"article_18-1.xml","purple_custom_meta_purple_source_article":"article_18-1.xml","purple_source_issue":"March-2022","purple_custom_meta_purple_source_issue":"March-2022","purple_external_id":"March-2022-18-1","purple_custom_meta_purple_external_id":"March-2022-18-1","purple_issue_code":"|0000089651||","purple_custom_meta_purple_issue_code":"|0000089651||","purple_android_product":"com.focus.magazine.issue375","purple_custom_meta_purple_android_product":"com.focus.magazine.issue375","purple_ios_product":"com.focus.magazine.issue375","purple_custom_meta_purple_ios_product":"com.focus.magazine.issue375","purple_web_product":"","purple_custom_meta_purple_web_product":"","purple_publication_id":"0f422ad1-c939-476d-9f82-a410052ad4c3","purple_migrated":"","kt_blocks_editor_width":"","apple_news_api_created_at":"2022-03-11T11:24:40Z","apple_news_article-theme":"","apple_news_api_id":"49a71455-a9d3-48b5-b756-07109fcfe0b5","apple_news_api_modified_at":"2022-03-23T09:16:08Z","apple_news_api_revision":"AAAAAAAAAAAAAAAAAAAABw==","apple_news_api_share_url":"https:\/\/apple.news\/ASacUVanTSLW3VgcQn8_gtQ","apple_news_coverimage":0,"apple_news_coverimage_caption":"","apple_news_is_hidden":false,"apple_news_is_paid":true,"apple_news_is_preview":true,"apple_news_is_sponsored":false,"apple_news_maturity_rating":"","apple_news_pullquote":"","apple_news_pullquote_position":"","apple_news_article_theme":"","apple_news_sections":"[]"},"categories":[25],"tags":[15],"apple_news_notices":[],"featured_image_src":"https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a.jpg","author_info":{"display_name":"importmanagerhub@sprylab.com","author_link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/author\/importmanagerhubsprylab-com\/"},"acf":{"readingTimeMinutes":"2","apple_news_title":""},"uagb_featured_image_src":{"full":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a.jpg",2048,1239,false],"thumbnail":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-150x150.jpg",150,150,true],"medium":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-300x181.jpg",300,181,true],"medium_large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-768x465.jpg",768,465,true],"large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-1024x620.jpg",800,484,true],"1536x1536":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a-1536x929.jpg",1536,929,true],"2048x2048":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/03\/6f095b29-de39-4f1f-9a1a-201dcecf574a.jpg",2048,1239,false]},"uagb_author_info":{"display_name":"importmanagerhub@sprylab.com","author_link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/author\/importmanagerhubsprylab-com\/"},"uagb_comment_info":0,"uagb_excerpt":"The chemical may drive reactions that produce organic 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