{"id":36281,"date":"2023-11-18T11:00:00","date_gmt":"2023-11-18T10:00:00","guid":{"rendered":"http:\/\/6063af23-6953-4f31-9390-ea26e864299a"},"modified":"2023-11-18T11:46:17","modified_gmt":"2023-11-18T10:46:17","slug":"this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution","status":"publish","type":"rss_feed","link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/rss_feed\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution\/","title":{"rendered":"This bold psychedelic and VR fusion therapy could spark a mental health revolution"},"content":{"rendered":"<p class=\"rssexcerpt\">Psychologists are exploring ways of treating mental health disorders by combining psychedelics and virtual reality. <\/p><p class=\"rssauthor\">By Dean Burnett\n      <\/p><p class=\"rssbyline\">Published: Saturday, 18 November 2023 at 10:00 AM<\/p><hr class=\"no-tts wp-block-separator\"\/><?xml version=\"1.0\" encoding=\"UTF-8\" standalone=\"yes\"?>\n<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\n<html><body><p>How would you go about changing your reality? There are many options available to the modern human, with varying degrees of permanence and legality. But perhaps the simplest method is to find a place where reality is different to what you\u2019re used to, and go there.<\/p><p>I tried this option in November 2022, by attending the Wonderland International Psychedelics conference and exhibition in Miami. \u00a0<\/p><p>As a Welsh neuroscientist from the Cardiff suburbs, with no involvement with\/experience of class-A drugs, exploring an international conference dedicated to them in the heart of a humid US city was, to put it mildly, outside my usual comfort zone. \u00a0<\/p><h2 id=\"h-psychedelics-is-a-big-industry\">Psychedelics is a big industry<\/h2><p>I was, admittedly, already aware of the ever-increasing evidence for the enormous potential of <a href=\"https:\/\/www.openaccessgovernment.org\/article\/psychedelic-therapies-psychiatry-mental-illness-psilocybin\/155265\/\" target=\"_blank\" rel=\"noreferrer noopener\">psychedelics to treat multiple mental health conditions<\/a>, hence I was keen to attend the event. What I wasn\u2019t aware of, however, was the whole industry that\u2019s built up around them as a result, which has led to many people taking psychedelics in many intriguing (if sometimes baffling) directions.<\/p><p>One that caught my eye at Wonderland was by <a href=\"https:\/\/www.enosistherapeutics.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">Enosis Therapeutics<\/a>, who generously allowed me to experience their AnchoringVR set-up. The brainchild of researcher <a href=\"https:\/\/www.enosistherapeutics.com\/team\" target=\"_blank\" rel=\"noreferrer noopener\">Agnieszka Sekula<\/a>, at first glance it appeared to be a virtual reality (VR) simulation of a surprisingly pleasant and realistic moonlit beach environment.\u00a0<\/p><p>The beach was sprinkled with floating star-like objects, which you could (via the relevant hand controls) pick up and speak into. Anything you said while holding the star would be recorded and saved for retrieval and replay later. Alternatively, you could throw these stars, and their associated\u00a0audio logs, into the ever-burning campfire present in the scenario.\u00a0<\/p><p>All very nice and relaxing sounding, but what does it have to do with psychedelics? Or mental health?\u00a0<\/p><p>In a sense, everything. <\/p><p>Because this is just one example of an interesting and unexpected new approach to treating mental health problems: combining psychedelics and virtual reality.\u00a0<\/p><hr class=\"wp-block-separator has-alpha-channel-opacity\"\/><p><strong>WARNING\u00a0<\/strong><\/p><p><em>Psychedelics, such as \u2018magic mushrooms\u2019 and LSD, are Class A drugs according to UK law. Anyone caught in possession of such substances can face up to seven years in prison, an unlimited fine, or both. Information and support for those affected by substance abuse can be found at <a href=\"http:\/\/bit.ly\/drug_support\" target=\"_blank\" rel=\"noreferrer noopener\">bit.ly\/drug_support<\/a><\/em> <\/p><hr class=\"wp-block-separator has-alpha-channel-opacity\"\/><h2 id=\"h-humans-have-been-taking-psychedelics-for-9-000-years\">Humans have been taking psychedelics for 9,000 years<\/h2><p>Combining <a href=\"https:\/\/www.sciencefocus.com\/science\/psychedelics\">psychedelics<\/a> and VR may seem like a strange notion, because, in many ways, psychedelics and VR couldn\u2019t be more different.\u00a0 \u00a0<\/p><p>For one thing, psychedelics are, to put it mildly, \u2018old school\u2019. You\u2019d be forgiven for assuming that psychedelics had the biggest impact on our culture during the \u2018Psychedelic era\u2019 during the 1960s and 70s. But actually, humankind\u2019s enthusiasm for psychedelics goes back considerably further.\u00a0<\/p><figure class=\"wp-block-image size-large\"><figcaption class=\"wp-element-caption\">Certain species of mushrooms contain the psychoactive compound psilocybin which can induce psychedelic experiences &#8211; Photo credit: Alamy<\/figcaption><\/figure><p>Psychedelics occur naturally in the wild. They can be found in <a href=\"https:\/\/druginfo.sl.nsw.gov.au\/drugs\/z-drugs\/natural-hallucinogens\" target=\"_blank\" rel=\"noreferrer noopener\">mushrooms, cacti, leaves, stems and more<\/a>, and for most of our history, humans survived by eating things that grew in the wild. As a consequence, humans have been consuming psychedelics for a very long time. <\/p><p>Tribal rituals involving psychedelics took place as far back as 9,000 years ago. Ergo, humans have been taking psychedelics for literally thousands of years. It\u2019s why they\u2019re so heavily intertwined with rituals and traditions concerning spirituality, mysticism and religion.<\/p><p>None of this applies to VR, however, which is an entirely modern phenomenon. Granted, it has existed in some form since the 1970s, or possibly even the 1950s, but that\u2019s about it.\u00a0<\/p><p>This is because VR can only exist in the context of modern technology. And as technology has improved, so has interest in VR and its possible applications.<\/p><p>Rather than spirituality and mysticism, VR has historically had more practical applications. NASA has used VR for training purposes for decades, as have various militaries. And it\u2019s constantly threatening to be the next big thing in video gaming. \u00a0<\/p><figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/c02.purpledshub.com\/uploads\/sites\/41\/2023\/11\/NASA-astronaut-Megan-McArthur-1024x682.jpg?fit=800%2C533\" alt=\"A photograph of NASA astronaut Megan McArthur in zero gravity\" class=\"wp-image-176061\" data-recalc-dims=\"1\"\/><figcaption class=\"wp-element-caption\">NASA astronaut Megan McArthur taking part in an experiment in which she attempts to operate a robotic arm via VR controls &#8211; Photo credit: NASA<\/figcaption><\/figure><p>So, psychedelics and VR have little in common. Unless you count the whole \u2018altering the reality we perceive\u2019 aspect. But even here, they go about it in radically different ways.\u00a0<\/p><p>In a very oversimplified nutshell, psychedelics are biological molecules that interact with certain neuron receptors. This leads to suppression of the brain\u2019s default mode network, the underlying system seemingly crucial for your sense of \u2018self\u2019, for internal modes of cognition. <\/p><p>Shutting this network down means your internal processes become mixed up, they overlap, and blur, and your ability to recognise where you are in time and space is compromised.\u00a0<\/p><ul><li><a href=\"https:\/\/www.sciencefocus.com\/the-human-body\/instant-genius-podcast-emotions-with-dr-dean-burnett\">Listen to Dr Dean Burnett on the <em>Instant Genius<\/em> Podcast talking about how to better cope with negative emotions<\/a><\/li><\/ul><h2 id=\"h-virtual-reality-is-100-per-cent-controllable\">Virtual reality is 100 per cent controllable<\/h2><p>VR, in contrast, leaves the inner workings of your brain well alone. Instead, it blocks out the external sensory environment (to a greater or lesser extent) and substitutes it with a synthetic, technologically generated one.\u00a0<\/p><p>While a less \u2018profound\u2019 experience than that provided by psychedelics, VR offers an alternative reality that\u2019s 100 per cent controllable, and tailor-made to suit the situation. <\/p><p>What if we eventually advance to a point where VR environments are indistinguishable from objective reality? While having none of the restrictions, not even the sky\u2019s the limit for what we could experience with it.\u00a0<\/p><p>Psychedelics and VR are both means of altering reality but with radically different origins, histories, associations and mechanisms of action. <\/p><p>However, contrary to what most people might assume due to the scaremongering surrounding them, the properties of both psychedelics and VR mean that they have significant scope to have a positive impact on mental health.<\/p><h2 id=\"h-psychedelics-make-the-brain-more-flexible\">Psychedelics make the brain more flexible<\/h2><p>It&#8217;s likely the \u2018recreational\u2019 aspects of a \u2018trip\u2019 are what most psychedelic enthusiasts are interested in. But scientists are interested in how they make the brain\u2019s internal workings more flexible, malleable and interconnected. <\/p><p>How psychedelics can make it easier to tackle the unhelpful patterns of thought that underlie mental health problems, which are often deeply ingrained into a person&#8217;s mind.<\/p><p>Psychedelics have a therapeutic potential that\u2019s increasingly hard to ignore. The existence of a three-day conference and exhibition dedicated to them is a stark demonstration of this. As is the recent move by a number of US states (including Oregon and Colorado) to decriminalise the use of psychedelics for therapy research. Likewise, in the case of Australia, to legalise them for prescribed medicinal use.\u00a0<\/p><p>It\u2019s quite a turnaround when you consider that, barely a decade ago, psychedelics were some of the most restricted drugs around, due to being a casualty of the War on Drugs.\u00a0<\/p><h2 id=\"h-modern-benefits-for-mental-health\">Modern benefits for mental health<\/h2><p>Similarly, that modern screen-based technology could be beneficial for mental health may also seem counterintuitive. After all, aren\u2019t we constantly being warned about the damage screen time and smartphone use are doing to our mental wellbeing?<\/p><p>While there is certainly a discussion (preferably an evidence-based one) to be had about such concerns, modern technology has been an increasingly common aspect of mental healthcare for some time now.\u00a0<\/p><p>Technology that offers <a href=\"https:\/\/www.mayoclinic.org\/tests-procedures\/biofeedback\/about\/pac-20384664\" target=\"_blank\" rel=\"noreferrer noopener\">bio-feedback<\/a> or <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4892319\/\" target=\"_blank\" rel=\"noreferrer noopener\">neuro-feedback<\/a> allows a patient to observe the anomalous things occurring in their body and brain during an <a href=\"https:\/\/www.sciencefocus.com\/the-human-body\/anxiety\">anxiety<\/a> attack. It gives them something more \u2018concrete\u2019 to try and get under control.\u00a0<\/p><h2 id=\"h-digital-therapy\">Digital therapy<\/h2><p>We now have digital or online therapies, allowing patients in need to access help remotely via their devices. This relieves pressure and demands on both patients and health services, and such things are now <a href=\"https:\/\/www.nice.org.uk\/news\/article\/eight-digitally-enabled-therapies-to-treat-depression-and-anxiety-in-adults-conditionally-recommended-by-nice\" target=\"_blank\" rel=\"noreferrer noopener\">recommended in official guidelines<\/a>.\u00a0<\/p><p>There\u2019s also <a href=\"https:\/\/www.ucl.ac.uk\/news\/2017\/nov\/avatar-therapy-reduce-auditory-hallucinations-people-schizophrenia\" target=\"_blank\" rel=\"noreferrer noopener\">avatar therapy<\/a>, which creates a helpful and reassuring virtual \u2018source\u2019 for a patient\u2019s psychotic audio hallucinations.<\/p><p>All of these things, and many more, are increasingly common means of treating mental health problems, and all are 100 per cent dependent on modern technology.<\/p><p>It\u2019s perhaps unsurprising then, that VR is also becoming an increasingly common therapeutic tool. From allowing 100 per cent controllable and beneficially gradual exposure to the triggers of <a href=\"https:\/\/www.sciencefocus.com\/the-human-body\/phobias\" target=\"_blank\" rel=\"noreferrer noopener\">phobias<\/a> and <a href=\"https:\/\/www.ncmh.info\/2019\/10\/07\/virtual-reality-treatment-could-help-veterans-living-with-ptsd\/\" target=\"_blank\" rel=\"noreferrer noopener\">post-traumatic stress disorders (PTSD)<\/a>, to <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8743938\/\" target=\"_blank\" rel=\"noreferrer noopener\">rehabilitating dementia patients via more regulated environments.<\/a><\/p><p>It now seems that psychedelics and VR do have something in common: they both seem to have great potential as therapeutic tools for mental health. And if they were combined, maybe they\u2019d be even more effective.\u00a0<\/p><h2 id=\"h-combining-the-two\"><strong>Combining the two\u00a0<\/strong><\/h2><p>As Agnieszka Sekula explained to me at the Wonderland conference, the Enosis AnchoringVR setup is intended for patients who are just completing a psychedelic-assisted therapy session.\u00a0<\/p><figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/c02.purpledshub.com\/uploads\/sites\/41\/2023\/11\/Dr-Dean-Burnett-tries-AnchoringVR-1024x576.jpg?fit=800%2C450\" alt=\"A Photograph of the author of this article, Dr Dean Burnett, trying AnchoringVR\" class=\"wp-image-176038\" data-recalc-dims=\"1\"\/><figcaption class=\"wp-element-caption\">Dr Dean Burnett tries out the AnchoringVR experience while Agnieszka Sekula (centre) looks on. &#8211; Photo credit: Wonderland Miami Conference<\/figcaption><\/figure><p>This is where a patient takes a dose of psychedelics (usually psilocybin or MDMA) in the presence of a trained therapist. The psychedelic state allows for much greater cognitive flexibility and general positive emotion, increasing the impact of introspection, revelations, insights, and so on. All of which can be very beneficial for mental health conditions and have <a href=\"https:\/\/ec.europa.eu\/research-and-innovation\/en\/horizon-magazine\/psychedelics-paired-therapy-could-treat-chronic-mental-health-conditions#:~:text=Their active molecules bind with,for some, perhaps even forever.\" target=\"_blank\" rel=\"noreferrer noopener\">lasting positive impacts<\/a>.<\/p><p>But one concern is that the psychedelic state is temporary, and insights and progress acquired during it may not endure beyond it. After all, context is a big part of memory.\u00a0<\/p><h2 id=\"h-a-multisensory-experience\">A multisensory experience<\/h2><p>As Agnieszka explained, \u201cThe psychedelic experience is a multisensory, embodied, deeply immersive experience, which is difficult to put into words. Therefore, processing it through the method of talk therapy seems almost counterintuitive \u2013 and yet, this is the predominant approach to integration\u201d.<\/p><p>\u201cImmersive (VR) environments allow us to exploit all the senses in therapeutic engagement and give patients an opportunity to express themselves in a multisensory fashion. But also, and perhaps most importantly, they allow them to journey through their expressions, to explore, together with their therapist, the contents of their psyche\u201d<\/p><h2 id=\"h-like-video-games-you-can-save-your-progress\">Like video games, you can &#8216;save&#8217; your progress<\/h2><p>The Enosis AnchoringVR set-up immerses the patient in the previously mentioned beach scenario as they\u2019re recovering from their \u2018trip\u2019. Here, they can use the calming multisensory interface to record their insights while they\u2019re still fresh in the patient\u2019s mind, and revisit them, in the same rich context, at the next session, thus better retaining and building on them.\u00a0<\/p><p>It\u2019s a similar idea to the \u2018checkpoints\u2019 you often encounter in video games that let you save your progress, so you don\u2019t have to start all over again each time. This approach essentially provides the same thing for therapy, complete with the advanced graphics!<\/p><figure class=\"wp-block-image size-large\"><img decoding=\"async\" loading=\"lazy\" src=\"https:\/\/c02.purpledshub.com\/uploads\/sites\/41\/2023\/11\/Guided-therapy-1024x682.jpg?fit=800%2C533\" alt=\"A photograph of a women in a chair undergoing guided VR therapy\" class=\"wp-image-176049\" data-recalc-dims=\"1\"\/><figcaption class=\"wp-element-caption\">Patients undergoing psychedelic therapy are typically guided through the treatment sessions with music or audio cues &#8211; Image credit: Getty images<\/figcaption><\/figure><p>VR can also be useful at the start of psychedelic therapy. Because it\u2019s such a powerful intervention, psychedelic therapy must be carefully managed. This includes creating the right \u2018setting\u2019 to put patients in a suitably positive frame of mind, because psychedelics combined with a negative headspace lead to a \u2018bad trip\u2019 \u2013 not helpful for someone already dealing with poor mental health.<\/p><p>If the initial environment is important for psychedelic therapy, VR, offering a 100 per cent controllable environment, may well <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2022.813746\/full\" target=\"_blank\" rel=\"noreferrer noopener\">make things much easier for both patient and therapist<\/a>. There are <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fpsyg.2022.813746\/full\" target=\"_blank\" rel=\"noreferrer noopener\">an increasing number of techniques incorporating VR and psychedelics<\/a>, or altered consciousness, with increasingly interesting approaches.\u00a0<\/p><h2 id=\"h-what-are-the-downsides\">What are the downsides?<\/h2><p>Some may think this all a bit unlikely. After all, as good as it may be, modern VR is still readily identifiable as artificial. Could it really have such tangible effects on people?\u00a0<\/p><p>Sure it can. After all, VR motion sickness is definitely a thing, revealing that, while we may consciously recognise VR as artificial, the subconscious processes that do most of the brain\u2019s heavy lifting are perfectly willing to accept it, certainly enough to immediately affect what\u2019s happening in the user\u2019s body.<\/p><p>Of course, it\u2019s still very early days for this intriguing combination of therapeutic interventions. There are still issues to be addressed, such as how psychedelics are very powerful therapeutic tools that need to be used carefully, under professional supervision. Or how effective VR requires much technological support and investment, in terms of both resources and expertise.\u00a0<\/p><h2 id=\"h-wouldn-t-they-just-be-better-on-their-own\">Wouldn&#8217;t they just be better on their own?<\/h2><p>There are also those who contend that psychedelic therapy is sufficient in its own right, and including VR in the process is an unnecessary distraction.\u00a0<\/p><p>Conversely, there are studies which suggest that a therapeutic psychedelic state can be induced via VR alone, removing the need for consumption of potent chemicals. Overall, though, psychedelics and VR represent an interesting, combined-therapy approach and we\u2019re only beginning to explore its potential.\u00a0<\/p><p>Ultimately, most mental health disorders come about via the things we experience, via the sights, sounds and internal cogitations our brains end up dealing with. If therapists were able to cause the afflicted brains to perceive and experience things that counteracted the things that led to mental health issues, treating them would potentially be a lot easier.<\/p><p>Psychedelics and VR have the potential to offer exactly that. And if we keep combining the two, who knows what we\u2019ll see?\u00a0<\/p><p><strong>Read more: <\/strong><\/p><ul><li><a href=\"https:\/\/www.sciencefocus.com\/news\/psychedelic-ingredient-in-magic-mushrooms-makes-music-more-emotional-to-our-brain\">Psychedelic ingredient in magic mushrooms makes music more emotional to our brain<\/a><\/li><li><a href=\"https:\/\/www.sciencefocus.com\/the-human-body\/what-near-death-experiences-could-tell-us-about-dying\">To death and back: what near-death experiences could tell us about dying<\/a><\/li><li><a href=\"https:\/\/www.sciencefocus.com\/news\/psychedelic-compound-found-in-magic-mushrooms-may-help-with-anxiety-and-depression-in-cancer-patients\">Psychedelic compound found in magic mushrooms may help with anxiety and depression in cancer patients<\/a><\/li><\/ul> <\/body><\/html>\n<hr class=\"no-tts wp-block-separator\"\/>","protected":false},"excerpt":{"rendered":"<p>Psychologists are exploring ways of treating mental health disorders by combining psychedelics and virtual reality. <\/p>\n","protected":false},"author":24,"featured_media":36282,"template":"","categories":[1],"acf":{"readingTimeMinutes":"11"},"uagb_featured_image_src":{"full":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2023\/11\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution.jpg",1280,960,false],"thumbnail":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2023\/11\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution-150x150.jpg",150,150,true],"medium":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2023\/11\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution-300x225.jpg",300,225,true],"medium_large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2023\/11\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution-768x576.jpg",768,576,true],"large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2023\/11\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution-1024x768.jpg",800,600,true],"1536x1536":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2023\/11\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution.jpg",1280,960,false],"2048x2048":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2023\/11\/this-bold-psychedelic-and-vr-fusion-therapy-could-spark-a-mental-health-revolution.jpg",1280,960,false]},"uagb_author_info":{"display_name":"importmanagerhub@sprylab.com","author_link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/author\/importmanagerhubsprylab-com\/"},"uagb_comment_info":0,"uagb_excerpt":"Psychologists are exploring ways of treating mental health disorders by combining psychedelics and virtual reality.","_links":{"self":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/rss_feed\/36281"}],"collection":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/rss_feed"}],"about":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/types\/rss_feed"}],"author":[{"embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/users\/24"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/media\/36282"}],"wp:attachment":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/media?parent=36281"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/categories?post=36281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}