{"id":914,"date":"2022-01-12T20:00:45","date_gmt":"2022-01-12T19:00:45","guid":{"rendered":"https:\/\/www.sciencefocus.com\/?p=108998"},"modified":"2022-01-12T20:44:11","modified_gmt":"2022-01-12T19:44:11","slug":"knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial","status":"publish","type":"rss_feed","link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/rss_feed\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial\/","title":{"rendered":"Knee cartilage regrown in rabbits using electric nanomaterial"},"content":{"rendered":"<p class=\"rssexcerpt\"><\/p><p class=\"rssauthor\">By Jason Goodyer\n                \t\t<\/p><p class=\"rssbyline\">Published: Wednesday, 12 January 2022 at 12:00 am<\/p><hr class=\"no-tts wp-block-separator\"\/><?xml version=\"1.0\" encoding=\"UTF-8\" standalone=\"yes\"?>\n<!DOCTYPE html PUBLIC \"-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\" \"http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\">\n<html><body><div class=\"&quot;image-handler__container\" image-handler__container--full=\"\" style=\"&quot;padding-bottom:\" calc=\"\"> <picture><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?webp=true&amp;quality=90&amp;resize=300%2C134,\" https:=\"\" type=\"&quot;image\/webp&quot;\"><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=300%2C134,\" https:=\"\" type=\"&quot;image\/png&quot;\"><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?webp=true&amp;quality=90&amp;resize=355%2C159,\" https:=\"\" type=\"&quot;image\/webp&quot;\"><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=355%2C159,\" https:=\"\" type=\"&quot;image\/png&quot;\"><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?webp=true&amp;quality=90&amp;resize=405%2C181,\" https:=\"\" type=\"&quot;image\/webp&quot;\"><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=405%2C181,\" https:=\"\" type=\"&quot;image\/png&quot;\"><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?webp=true&amp;quality=90&amp;resize=554%2C248,\" https:=\"\" type=\"&quot;image\/webp&quot;\"><source media=\"&quot;(max-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=554%2C248,\" https:=\"\" type=\"&quot;image\/png&quot;\"><source media=\"&quot;(min-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?webp=true&amp;quality=90&amp;resize=620%2C277,\" https:=\"\" type=\"&quot;image\/webp&quot;\"><source media=\"&quot;(min-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=620%2C277,\" https:=\"\" type=\"&quot;image\/png&quot;\"><source media=\"&quot;(min-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?webp=true&amp;quality=90&amp;resize=408%2C182,\" https:=\"\" type=\"&quot;image\/webp&quot;\"><source media=\"&quot;(min-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=408%2C182,\" https:=\"\" type=\"&quot;image\/png&quot;\"><source media=\"&quot;(min-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?webp=true&amp;quality=90&amp;resize=556%2C248,\" https:=\"\" type=\"&quot;image\/webp&quot;\"><source media=\"&quot;(min-width:\" data-srcset=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=556%2C248,\" https:=\"\" type=\"&quot;image\/png&quot;\"><img class=\"&quot;wp-image-109000\" align=\"\" size-full=\"\" image-handler__image=\"\" image-handler__image--full=\"\" no-wrap=\"\" js-lazyload=\"\" data-src=\"&quot;https:\/\/images.immediate.co.uk\/production\/volatile\/sites\/4\/2022\/01\/Screenshot-2022-01-12-at-14.10.00-4631cab.png?quality=90&amp;resize=620%2C277&quot;\" width=\"&quot;620&quot;\" height=\"&quot;277&quot;\" alt=\"&quot;The\" plla=\"\" stimulated=\"\" growth=\"\" in=\"\" the=\"\" rabbit=\"\" cartilage=\"\" when=\"\" it=\"\" exercised=\"\" on=\"\" a=\"\" treadmill=\"\" thanh=\"\" nguyen=\"\" of=\"\" connecticut=\"\" title=\"&quot;The\"\/><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/source><\/picture><\/div><div class=\"&quot;caption-hold&quot;\"><figcaption class=\"&quot;wp-caption-text&quot;\"><span class=\"&quot;caption-copy&quot;\"><i class=\"&quot;icon-arrow\" icon-camera-circle=\"\"\/> The implant stimulated growth in the rabbit\u2019s cartilage when it exercised on a treadmill \u00a9 Thanh Nguyen\/University of Connecticut<\/span><\/figcaption><span class=\"&quot;im-image-caption&quot;\"\/><\/div>\n<p>This bunny could hold the key to fixing your bum knee. Researchers at the University of Connecticut have successfully regrown damaged cartilage in a rabbit\u2019s knee joint using biodegradable polymers with a nifty electric property.<\/p>\n<p>It is currently estimated that around 10 per cent of the UK\u2019s population have been diagnosed with arthritis, a disease that causes the pads of cartilage that cushion our joints to deteriorate.<\/p>\n<p>Eventually, it can lead to cartilage becoming so worn down that bone begins to grind on bone, making everyday activities such as walking extremely painful.<\/p>\n<p>Current treatments involve physiotherapy and painkillers, but severe cases often require surgery to replace damaged cartilage using a healthy piece taken from elsewhere in the body, or from a donor.<\/p>\n<p>Now, a team led by bioengineer <a href=\"\/\/me.engr.uconn.edu\/blog\/faculty\/nguyen-thanh-duc\/&quot;\" target=\"&quot;_blank&quot;\" rel=\"&quot;noopener&quot; noopener noreferrer\">Thanh Nguyen<\/a> have designed a treatment that uses electrical signals to stimulate cartilage regeneration.<\/p>\n<p>They implanted a tissue scaffold made out of nanofibres of poly-L lactic acid (PLLA), a biodegradable polymer often used to stitch up surgical wounds, into the knee of a rabbit with damaged cartilage.<\/p>\n<p>This material has a property known as piezoelectricity, which means it produces a small burst of electrical current when it is squished.<\/p>\n<p>Once the rabbit was placed onto a treadmill to exercise after receiving the implant, its hopping movements triggered the piezoelectric bursts in the PLLA which stimulated the cartilage to grow back.<\/p>\n<p>\u201cPiezoelectricity is a phenomenon that also exists in the human body. Bone, cartilage, collagen, DNA and various proteins have a piezoelectric response. Our approach to healing cartilage is highly clinically translational, and we will look into the related healing mechanism,\u201d said Dr Yang Liu, a postdoctoral fellow in Nguyen\u2019s group and the lead author of the study.<\/p>\n<p>The team now plan to observe the animals treated for a longer period and to apply the same technique to older animals to see if it is still as effective.<\/p>\n<p><strong>Read more about joint pain:<\/strong><\/p>\n<ul><li><a href=\"&quot;https:\/\/www.sciencefocus.com\/the-human-body\/why-do-joints-crack\/&quot;\">Why do joints crack?<\/a><\/li>\n<li><a href=\"&quot;https:\/\/www.sciencefocus.com\/the-human-body\/why-does-cold-weather-make-joints-sore\/&quot;\">Why does cold weather make joints sore?<\/a><\/li>\n<li><a href=\"&quot;https:\/\/www.sciencefocus.com\/the-human-body\/whats-the-best-painkiller\/&quot;\">What\u2019s the best painkiller?<\/a><\/li>\n<\/ul><\/body><\/html>\n<hr class=\"no-tts wp-block-separator\"\/>","protected":false},"excerpt":{"rendered":"<p>By Jason Goodyer Published: Wednesday, 12 January 2022 at 12:00 am The implant stimulated growth in the rabbit\u2019s cartilage when it exercised on a treadmill \u00a9 Thanh Nguyen\/University of Connecticut This bunny could hold the key to fixing your bum knee. Researchers at the University of Connecticut have successfully regrown damaged cartilage in a rabbit\u2019s [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":915,"template":"","categories":[1],"acf":{"readingTimeMinutes":"2"},"uagb_featured_image_src":{"full":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/01\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial.jpg",1200,757,false],"thumbnail":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/01\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial-150x150.jpg",150,150,true],"medium":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/01\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial-300x189.jpg",300,189,true],"medium_large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/01\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial-768x484.jpg",768,484,true],"large":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/01\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial-1024x646.jpg",800,505,true],"1536x1536":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/01\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial.jpg",1200,757,false],"2048x2048":["https:\/\/c01.purpledshub.com\/uploads\/sites\/42\/2022\/01\/knee-cartilage-regrown-in-rabbits-using-electric-nanomaterial.jpg",1200,757,false]},"uagb_author_info":{"display_name":"importmanagerhub@sprylab.com","author_link":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/author\/importmanagerhubsprylab-com\/"},"uagb_comment_info":0,"uagb_excerpt":"By Jason Goodyer Published: Wednesday, 12 January 2022 at 12:00 am The implant stimulated growth in the rabbit\u2019s cartilage when it exercised on a treadmill \u00a9 Thanh Nguyen\/University of Connecticut This bunny could hold the key to fixing your bum knee. Researchers at the University of Connecticut have successfully regrown damaged cartilage in a rabbit\u2019s&hellip;","_links":{"self":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/rss_feed\/914"}],"collection":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/rss_feed"}],"about":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/types\/rss_feed"}],"author":[{"embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/users\/24"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/media\/915"}],"wp:attachment":[{"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/media?parent=914"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/c01.purpledshub.com\/bbcsciencefocus\/wp-json\/wp\/v2\/categories?post=914"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}