By Morgan Cormack

Published: Sunday, 25 December 2022 at 12:00 am


Like clockwork, Call the Midwife fans have got used to visiting Nonnatus House at the most wonderful time of the year when the Christmas special rolls around.

Since 2012, viewers have come to expect dramatic and lighthearted comedic moments that leave us with our hearts positively warmed. And this year is no different.

The festive special returns to Poplar in 1967 following the previous year’s devastating train crash. As well as the midwives moving into a brand new maternity clinic, Trixie (Helen George) has made an anticipated return from Portofino.

But like any good Call the Midwife episode, the 1 hour and 29 minute-long special also centres around a pressing maternity issue.

The theme of thalidomide poisoning is woven throughout the episode as fan-favourite character Rhoda Mullucks (Liz White) returns to the show. This time round, she’s heavily pregnant and nervous about her unborn child as her first daughter, who was born in season 5, lives with limbs that have been affected by thalidomide.

But what is the drug exactly? What was it used for and how did it come to be at the centre of such tragedy?

What is thalidomide?

""
Liz White as Rhoda Mullucks in Call the Midwife Christmas special.
BBC, Neal Street Productions, Olly Courtenay

Thalidomide has been sold under the names Contergan and Thalomid among many others, but the drug was initially marketed back in 1957 in West Germany.

The oral medication was promoted for easing anxiety, sleeping troubles, morning sickness and tension. Subsequently, the drug was soon prescribed to many pregnant women to combat severe morning sickness.

The drug became licensed in the UK in 1958 but was eventually withdrawn in 1961.

Today, thalidomide is used as a treatment for leprosy and cancers such as multiple myeloma.

Speaking previously to RadioTimes.com about the inclusion of the topic in season 5, actor Stephen McGann, who plays Dr Patrick Turner, told us: “The sense of responsibility with covering something so big and so important as thalidomide was felt by everybody at all levels in the production.

“For the actors, it was very easy for us to see just how much this meant, how much care needed to be taken and everybody has to step up for that. We still feel that because with the theme of thalidomide there is still more of the story to be unfolded.”

How did thalidomide affect pregnancies?

Behind the Scenes on the #CallTheMidwife Christmas Special: The Mullocks family at Christmas ❤️https://t.co/j2JtA08d94 pic.twitter.com/9KN0w5AtEB

— Call the Midwife (@CallTheMidwife1) December 14, 2022