The new Netflix series explores the opioid drug crisis that still ravages America to this day.

By Morgan Cormack

Published: Tuesday, 08 August 2023 at 13:25 PM


New Netflix drama Painkiller is set to be the platform’s next talked-about watch as it explores the very real opioid crisis in America through fictional characters who are personally dealing with it – and those taking on the family behind Purdue Pharma, the Sacklers.

While the drama is based on Barry Meier’s book Pain Killer: An Empire of Deceit and the Origin of America’s Opioid Epidemic, and a New Yorker Magazine article, The Family That Built an Empire of Pain, by Patrick Radden Keefe, Painkiller is a fictionalised retelling of events.

Some of those fictional characters, who also help to give a voice to those dealing with addiction and the legal ramifications of the crisis, include Evie Flowers (played by Uzo Aduba) and Glen Kryger (Taylor Kitsch), as well as West Duchovny as Shannon Schaeffer and Matthew Broderick as Richard Sackler.

But who exactly do they play in the new series and where have you seen them before? Read on for everything you need to know about the cast of Painkiller.

Painkiller cast: All the characters and actors in Netflix drama

The new Netflix drama is home to some stellar performances with the actors listed below. Scroll on to find out more about their characters and where you’ve seen the actors before.

Uzo Aduba plays Edie Flowers

Painkiller - Netflix
Painkiller: Uzo Aduba as Edie Flowers.
Netflix

Who is Edie Flowers? Edie is a no-nonsense lawyer who is working for the US Attorney’s office when, one day, she happens to notice a pattern in prescriptions for OxyContin.

Where have I seen Uzo Aduba? Aduba is perhaps best known for her role as Suzanne ‘Crazy Eyes’ Warren in Netflix’s Orange is the New Black, but has also starred in Mrs America, Lightyear, In Treatment and Solos, to name a few.

Matthew Broderick plays Richard Sackler

Painkiller - Netflix
Painkiller: Matthew Broderick as Richard Sackler.
Keri Anderson/Netflix

Who is Richard Sackler? Richard steps up in the Sackler family and becomes chairman and president of Purdue Pharma, prompting the major call to replace MS Contin with OxyContin and pushing the narrative that OxyContin was not highly addictive.

Where have I seen Matthew Broderick? Broderick is known for a number of roles over the years, from 1986’s Ferris Bueller’s Day Off, being the voice of Simba in the original Lion King movie, WarGames, Godzilla and Inspector Gadget.

Broderick also has an illustrious Broadway career, having won two Tony Awards, and more recently starring in a Broadway revival of Plaza Suite alongside wife Sarah Jessica Parker.

Taylor Kitsch plays Glen Kryger

Painkiller - Netflix
Painkiller: Taylor Kitsch as Glen Kryger.
Keri Anderson/Netflix

Who is Glen Kryger? Glen is a small business owner and hardworking family man. But when he gets injured at work, his doctor soon prescribes him a new miracle drug, OxyContin, and we follow his journey as the drug upends him and his family.

Where have I seen Taylor Kitsch? Kitsch is best known for his role as Tim Riggins in the NBC TV series Friday Night Lights, but has also starred in a number of thrillers including True Detective, The Terminal List, 21 Bridges and Waco.

West Duchovny plays Shannon Schaeffer

Painkiller - Netflix
Painkiller: West Duchovny as Shannon Shaeffer.
Keri Anderson/Netflix

Who is Shannon Schaeffer? Shannon has just left university and doesn’t exactly want to move back in with her parents and have a dead-end job. So when she attends a recruitment drive for Purdue Pharma, she sees the future she could have – one that includes money, fast cars and persuading doctors to prescribe OxyContin.

Where have I seen West Duchovny? Duchovny has most recently led the cast of Hulu’s Saint X, but has also starred in The Magician and has appeared alongside her father David Duchovny in a 2018 episode of The X Files.

Dina Shihabi plays Britt Hufford

Painkiller - Netflix
Painkiller: (L to R) West Duchovny as Shannon Shaeffer, Dina Shihabi as Britt Hufford.
Keri Anderson/Netflix

Who is Britt Hufford? Britt is a veteran Purdue Pharma sales rep and recruits Shannon quickly, showing her the luxurious life she could have.

Where have I seen Dina Shihabi? Shihabi has appeared in numerous TV shows including Jack Ryan, Altered Carbon, Archive 81 and more recently in Showtime’s Ghosts of Beirut.

Tyler Ritter plays US Attorney John Brownlee

Painkiller - Netflix
Painkiller: (L to R) Tyler Ritter as John Brownlee, Uzo Aduba as Edie.
Keri Anderson/Netflix

Who is US Attorney John BrownleeJohn is Edie’s newly appointed and very clean-cut boss who takes note of her Purdue Pharma findings, prompting a legal battle to pursue justice and the truth behind OxyContin.

Where have I seen Tyler Ritter? Ritter has starred in The McCarthys, Young and Hungry and Arrow, as well as having guest roles in Modern Family, Grey’s Anatomy and Homecoming.

Carolina Bartczak plays Lily Kryger

Painkiller - Netflix
Painkiller: (L to R) Taylor Kitsch as Glen Kryger, Carolina Bartczak as Lily Kryger.
Keri Anderson/Netflix

Who is Lily Kryger? Lily is Glen’s wife and works alongside him at the garage. But when he suffers a devastating injury and struggles with OxyContin usage, she has to face up to the reality of his addiction.

Where have I seen Carolina Bartczak? Bartczak is known for her role as Magda Lehnsherr, the wife of Erik Lehnsherr/Magneto, in X-Men: Apocalypse – but has also had roles in The Bold Type, Moonfall, Most Dangerous Game and The Secret Life of Marilyn Monroe.

Jack Mulhern plays Tyler Kryger

Painkiller - Netflix
Painkiller: Jack Mulhern as Tyler Kryger.
Netflix

Who is Tyler Kryger? Tyler is Lily’s teenage son and Glen’s step-son, who is involved in Glen’s accident and blames himself. But among his friends, he soon starts to see the lure of OxyContin in his age group.

Where have I seen Jack Mulhern? Mulhern has starred in Mare of Easttown, The Society, Wu-Tang: An American Saga, Unconformity and Odd Man Rush.

Clark Gregg plays Arthur Sackler

Painkiller - Netflix
Painkiller: Clark Gregg as Arthur Sackler.
Netflix

Who is Arthur SacklerArthur is the patriarch of the Sacklers and the original founder of Purdue. But when Richard takes up the reins, he is followed by a vision of Arthur who helps guide him through their family legacy.

Where have I seen Clark Gregg? Gregg is perhaps best known for portraying Agent Phil Coulson in various Marvel Cinematic Universe films and series, as well as starring in The West Wing, How I Met Your Father, Will & Grace, 500 Days of Summer and many more.